Exercise Science Dept.
815 North Broadway
Saratoga Springs, NY 12866
National Institute of Health -
Academic Research Enhancement Award
The primary scientific aim of the grant is to identify a cellular link between two devastating public health problems: sarcopenia and type 2 diabetes. Sarcopenia is a term used to describe the loss of muscle mass with advancing age and type 2 diabetes is a disease where insulin looses its ability to lower blood glucose. Similar to sarcopenia, individuals become more susceptible to type 2 diabetes with advancing age. Professor Reynolds is attempting to identify how changes in insulin’s ability to lower blood glucose could also play a role in the development of sarcopenia. The connection may be related to the activity of a protein termed Akt/PKB. Akt/PKB appears to be an essential protein for insulin to lower blood glucose and to prevent the breakdown of skeletal muscle tissue.